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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBR1 All Species: 10.91
Human Site: S619 Identified Species: 24
UniProt: Q16650 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16650 NP_006584.1 682 74053 S619 S S W I E T P S S I K S I D S
Chimpanzee Pan troglodytes XP_526157 702 74704 P639 S S W I E T P P S I K S L D S
Rhesus Macaque Macaca mulatta XP_001093085 737 80029 P674 S S W I E T P P S I K S L D S
Dog Lupus familis XP_545492 682 73929 S619 S S W I E T P S S I K S I D S
Cat Felis silvestris
Mouse Mus musculus Q64336 681 73923 S618 S S W I E T P S S I K S I D S
Rat Rattus norvegicus Q5I2P1 517 57726 Q457 G E G M F Q H Q T S V T H Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514679 386 42515 V326 E G E G S P P V W T E I A S V
Chicken Gallus gallus Q9PWE8 521 58384 Q460 T H S M F Q H Q T S V S H Q P
Frog Xenopus laevis P79944 692 75925 P631 S S W V E T P P S I K S L D S
Zebra Danio Brachydanio rerio Q9IAK8 492 55218 E430 F A S R Q M P E A H G M Y A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791266 946 105128 T885 A K H N Y P Q T N I H A Q S N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 49 46.8 99.2 N.A. 99.1 24.6 N.A. 30.3 24.4 50 25.5 N.A. N.A. N.A. N.A. 26.7
Protein Similarity: 100 64 60.5 99.5 N.A. 99.2 37.2 N.A. 38.1 36.5 65 37.5 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 86.6 86.6 100 N.A. 100 0 N.A. 6.6 6.6 80 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 93.3 100 N.A. 100 20 N.A. 13.3 26.6 93.3 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 10 0 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 % D
% Glu: 10 10 10 0 55 0 0 10 0 0 10 0 0 0 0 % E
% Phe: 10 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 10 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 10 10 0 0 0 19 0 0 10 10 0 19 0 0 % H
% Ile: 0 0 0 46 0 0 0 0 0 64 0 10 28 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 55 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 % L
% Met: 0 0 0 19 0 10 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 19 73 28 0 0 0 0 0 0 19 % P
% Gln: 0 0 0 0 10 19 10 19 0 0 0 0 10 19 0 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 55 55 19 0 10 0 0 28 55 19 0 64 0 19 64 % S
% Thr: 10 0 0 0 0 55 0 10 19 10 0 10 0 0 0 % T
% Val: 0 0 0 10 0 0 0 10 0 0 19 0 0 0 10 % V
% Trp: 0 0 55 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _